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RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1

Mutations in the gene encoding Ras-associated binding protein 23 (RAB23) cause Carpenter Syndrome, which is characterized by multiple developmental abnormalities including polysyndactyly and defects in skull morphogenesis. To understand how RAB23 regulates skull development, we generated Rab23-defic...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hasan, Md Rakibul, Takatalo, Maarit, Ma, Hongqiang, Rice, Ritva, Mustonen, Tuija, Rice, David PC
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423339/
https://ncbi.nlm.nih.gov/pubmed/32662771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55829
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