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RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1
Mutations in the gene encoding Ras-associated binding protein 23 (RAB23) cause Carpenter Syndrome, which is characterized by multiple developmental abnormalities including polysyndactyly and defects in skull morphogenesis. To understand how RAB23 regulates skull development, we generated Rab23-defic...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7423339/ https://ncbi.nlm.nih.gov/pubmed/32662771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55829 |
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