Prevention of Premature Fusion of Calvarial Suture in GLI-Kruppel Family Member 3 (Gli3)-deficient Mice by Removing One Allele of Runt-related Transcription Factor 2 (Runx2)

Mutations in the gene encoding the zinc finger transcription factor GLI3 (GLI-Kruppel family member 3) have been identified in patients with Grieg cephalopolysyndactyly syndrome in which premature fusion of calvarial suture (craniosynostosis) is an infrequent but important feature. Here, we show tha...

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Detalhes bibliográficos
Main Authors: Tanimoto, Yukiho, Veistinen, Lotta, Alakurtti, Kirsi, Takatalo, Maarit, Rice, David P. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375564/
https://ncbi.nlm.nih.gov/pubmed/22547067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362145
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