Loss-of-Function of Gli3 in Mice Causes Abnormal Frontal Bone Morphology and Premature Synostosis of the Interfrontal Suture

Greig cephalopolysyndactyly syndrome (GCPS) is an autosomal dominant disorder with polydactyly and syndactyly of the limbs and a broad spectrum of craniofacial abnormalities. Craniosynostosis of the metopic suture (interfrontal suture in mice) is an important but rare feature associated with GCPS. G...

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Detalhes bibliográficos
Main Authors: Veistinen, Lotta, Takatalo, Maarit, Tanimoto, Yukiho, Kesper, Dörthe A., Vortkamp, Andrea, Rice, David P. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342524/
https://ncbi.nlm.nih.gov/pubmed/22563320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00121
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