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Gli3(Xt−J/Xt−J) mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation
Gli3 is a zinc-finger transcription factor whose activity is dependent on the level of hedgehog (Hh) ligand. Hh signaling has key roles during endochondral ossification; however, its role in intramembranous ossification is still unclear. In this study, we show that Gli3 performs a dual role in regul...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916710/ https://ncbi.nlm.nih.gov/pubmed/20570969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq258 |
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