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Gli3(Xt−J/Xt−J) mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation

Gli3 is a zinc-finger transcription factor whose activity is dependent on the level of hedgehog (Hh) ligand. Hh signaling has key roles during endochondral ossification; however, its role in intramembranous ossification is still unclear. In this study, we show that Gli3 performs a dual role in regul...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Rice, David P.C., Connor, Elaine C., Veltmaat, Jacqueline M., Lana-Elola, Eva, Veistinen, Lotta, Tanimoto, Yukiho, Bellusci, Saverio, Rice, Ritva
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916710/
https://ncbi.nlm.nih.gov/pubmed/20570969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq258
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