RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation

Embryonic stem cells (ESC) maintain high genomic plasticity, essential for their capacity to enter diverse differentiation pathways. Post-transcriptional modifications of chromatin histones play a pivotal role in maintaining this plasticity. We now report that one such modification, monoubiquitylati...

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Autores principales: Fuchs, Gilad, Shema, Efrat, Vesterman, Rita, Kotler, Eran, Wolchinsky, Zohar, Wilder, Sylvia, Golomb, Lior, Pribluda, Ariel, Zhang, Feng, Haj-Yahya, Mahmood, Feldmesser, Ester, Brik, Ashraf, Yu, Xiaochun, Hanna, Jacob, Aberdam, Daniel, Domany, Eytan, Oren, Moshe
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374598/
https://ncbi.nlm.nih.gov/pubmed/22681888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.05.023
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