USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination

Recent reports have made important revelations, uncovering direct regulation of DNA damage response (DDR)-associated proteins and chromatin ubiquitination (Ubn) by macroautophagy/autophagy. Here, we report a previously unexplored connection between autophagy and DDR, via a deubiquitnase (DUB), USP14...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Sharma, Arishya, Alswillah, Turkeya, Singh, Kamini, Chatterjee, Payel, Willard, Belinda, Venere, Monica, Summers, Matthew K., Almasan, Alexandru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Research Paper - Basic Science
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152509/
https://ncbi.nlm.nih.gov/pubmed/29995557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1496877
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