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Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents
Prenyl- and pyrano-xanthones derived from 1,3,6-trihydroxy-9H-xanthen-9-one, a basic backbone of gambogic acid (GA), were synthesized and evaluated for in vitro cytotoxic effects against four human cancer cell lines (KB, KBvin, A549, and DU-145) and anti-inflammatory activity toward superoxide anion...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374489/ https://ncbi.nlm.nih.gov/pubmed/22595179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.04.084 |
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