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Antitumor Agents 281. Design, Synthesis, and Biological Activity of Substituted 4-Amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one Analogs (ATBO) as Potent In Vitro Anticancer Agents

In our exploration of new biologically active chemical entities, we designed and synthesized a novel class of antitumor agents, substituted 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one (ATBO) analogs. We evaluated their cytotoxic activity against seven human tumor cell lines from different t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dong, Yizhou, Nakagawa-Goto, Kyoko, Lai, Chin-Yu, Morris-Natschke, Susan L., Bastow, Kenneth F., Lee, Kuo-Hsiung
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053047/
https://ncbi.nlm.nih.gov/pubmed/21087859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.10.074
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