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Biochemical characterization of a SET and transposase fusion protein, Metnase (SETMAR) for its DNA binding and DNA cleavage activity

Metnase (SETMAR) is a SET and transposase fusion protein that promotes in vivo end joining activity and mediates genomic integration of foreign DNA. Recent studies showed that Metnase retained most of the transposase activities, including 5’-terminal inverted repeat (TIR)-specific binding and assemb...

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Bibliografiske detaljer
Main Authors: Roman, Yaritzabel, Oshige, Masahiko, Lee, Young-Ju, Goodwin, Kristie, Georgiadis, Millie M., Hromas, Robert A., Lee, Suk-Hee
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374406/
https://ncbi.nlm.nih.gov/pubmed/17877369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7005477
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