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Biochemical characterization of a SET and transposase fusion protein, Metnase (SETMAR) for its DNA binding and DNA cleavage activity

Metnase (SETMAR) is a SET and transposase fusion protein that promotes in vivo end joining activity and mediates genomic integration of foreign DNA. Recent studies showed that Metnase retained most of the transposase activities, including 5’-terminal inverted repeat (TIR)-specific binding and assemb...

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Autors principals: Roman, Yaritzabel, Oshige, Masahiko, Lee, Young-Ju, Goodwin, Kristie, Georgiadis, Millie M., Hromas, Robert A., Lee, Suk-Hee
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374406/
https://ncbi.nlm.nih.gov/pubmed/17877369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7005477
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