APL-1, the Alzheimer’s Amyloid Precursor Protein in Caenorhabditis elegans, Modulates Multiple Metabolic Pathways Throughout Development

Mutations in the amyloid precursor protein (APP) gene or in genes that process APP are correlated with familial Alzheimer’s disease (AD). The biological function of APP remains unclear. APP is a transmembrane protein that can be sequentially cleaved by different secretases to yield multiple fragment...

Full description

Saved in:
Bibliographic Details
Main Authors: Ewald, Collin Y., Raps, Daniel A., Li, Chris
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2012
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374313/
https://ncbi.nlm.nih.gov/pubmed/22466039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.138768
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items