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The secreted Alzheimer-related amyloid precursor protein fragment has an essential role in C. elegans

Mutations in the gene encoding the amyloid precursor protein (APP) or the enzymes that process APP are correlated with familial Alzheimer disease. Alzheimer disease is also associated with insulin resistance (type 2 diabetes). In our recently published study,(1) we obtained genetic evidence that the...

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Bibliografiske detaljer
Main Authors: Ewald, Collin Y., Li, Chris
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510856/
https://ncbi.nlm.nih.gov/pubmed/23044509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.22310
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