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Alzheimer‐related protein APL‐1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans

Alzheimer's disease (AD) is an age‐associated disease. Mutations in the amyloid precursor protein (APP) may be causative or protective of AD. The presence of two functionally redundant APP‐like genes (APLP1/2) has made it difficult to unravel the biological function of APP during aging. The nem...

詳細記述

保存先:
書誌詳細
出版年:Aging Cell
主要な著者: Ewald, Collin Y., Marfil, Vanessa, Li, Chris
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114704/
https://ncbi.nlm.nih.gov/pubmed/27557896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12509
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