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Alzheimer‐related protein APL‐1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans

Alzheimer's disease (AD) is an age‐associated disease. Mutations in the amyloid precursor protein (APP) may be causative or protective of AD. The presence of two functionally redundant APP‐like genes (APLP1/2) has made it difficult to unravel the biological function of APP during aging. The nem...

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Bibliografiset tiedot
Julkaisussa:Aging Cell
Päätekijät: Ewald, Collin Y., Marfil, Vanessa, Li, Chris
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114704/
https://ncbi.nlm.nih.gov/pubmed/27557896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12509
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