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Alzheimer‐related protein APL‐1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans

Alzheimer's disease (AD) is an age‐associated disease. Mutations in the amyloid precursor protein (APP) may be causative or protective of AD. The presence of two functionally redundant APP‐like genes (APLP1/2) has made it difficult to unravel the biological function of APP during aging. The nem...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Aging Cell
मुख्य लेखकों: Ewald, Collin Y., Marfil, Vanessa, Li, Chris
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114704/
https://ncbi.nlm.nih.gov/pubmed/27557896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12509
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