Pan-Neuronal Expression of APL-1, an APP-Related Protein, Disrupts Olfactory, Gustatory, and Touch Plasticity in Caenorhabditis elegans

Patients with Alzheimer's disease show age-related cognitive decline. Postmortem autopsy of their brains shows the presence of large numbers of senile plaques, whose major component is the β-amyloid peptide. The β-amyloid peptide is a cleavage product of the amyloid precursor protein (APP). In...

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Hlavní autoři: Ewald, Collin Y., Cheng, Ruby, Tolen, Lana, Shah, Vishal, Gillani, Aneela, Nasrin, Afsana, Li, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698849/
https://ncbi.nlm.nih.gov/pubmed/22836251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0495-12.2012
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