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Caenorhabditis elegans as a model organism to study APP function
The brains of Alzheimer's disease patients show an increased number of senile plaques compared with normal patients. The major component of the plaques is the β-amyloid peptide, a cleavage product of the amyloid precursor protein (APP). Although the processing of APP has been well-described, th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746071/ https://ncbi.nlm.nih.gov/pubmed/22038715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00221-011-2905-7 |
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