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Caenorhabditis elegans as a model organism to study APP function

The brains of Alzheimer's disease patients show an increased number of senile plaques compared with normal patients. The major component of the plaques is the β-amyloid peptide, a cleavage product of the amyloid precursor protein (APP). Although the processing of APP has been well-described, th...

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Hlavní autoři: Ewald, Collin Y., Li, Chris
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746071/
https://ncbi.nlm.nih.gov/pubmed/22038715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00221-011-2905-7
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