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APL-1, the Alzheimer’s Amyloid Precursor Protein in Caenorhabditis elegans, Modulates Multiple Metabolic Pathways Throughout Development

Mutations in the amyloid precursor protein (APP) gene or in genes that process APP are correlated with familial Alzheimer’s disease (AD). The biological function of APP remains unclear. APP is a transmembrane protein that can be sequentially cleaved by different secretases to yield multiple fragment...

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Sonraí Bibleagrafaíochta
Main Authors: Ewald, Collin Y., Raps, Daniel A., Li, Chris
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374313/
https://ncbi.nlm.nih.gov/pubmed/22466039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.138768
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