טוען...
Lipid Nanoparticles for Hepatic Delivery of Small Interfering RNA
Clinical application of small interfering RNA (siRNA) requires safe and efficient delivery in vivo. Here, we report the design and synthesis of lipid nanoparticles (LNPs) for siRNA delivery based on cationic lipids with multiple tertiary amines and hydrophobic linoleyl chains. LNPs incorporating the...
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| Main Authors: | , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374058/ https://ncbi.nlm.nih.gov/pubmed/22652024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.05.002 |
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