Cationic Lipid Nanoparticles for Therapeutic Delivery of siRNA and miRNA to Murine Liver Tumor

miR-122, a liver-specific tumor suppressor microRNA, is frequently downregulated in hepatocellular carcinoma (HCC). LNP-DP1, a cationic lipid nanoparticle formulation, was developed as a vehicle to restore deregulated gene expression in HCC cells by miR-122 delivery. LNP-DP1 consists of 2-dioleyloxy...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hsu, Shu-hao, Yu, Bo, Wang, Xinmei, Lu, Yuanzhi, Schmidt, Carl R., Lee, Robert J., Lee, L. James, Jacob, Samson T., Ghoshal, Kalpana
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3815988/
https://ncbi.nlm.nih.gov/pubmed/23727126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2013.05.007
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