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The Role of Alpha-Synuclein Oligomerization and Aggregation in Cellular and Animal Models of Parkinson’s Disease

α-synuclein (α-syn) is a synaptic protein in which four mutations (A53T, A30P, E46K and gene triplication) have been found to cause an autosomal dominant form of Parkinson’s disease (PD). It is also the major component of intraneuronal protein aggregates, designated as Lewy bodies (LBs), a prominent...

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Bibliografske podrobnosti
Main Authors: Wan, Oi Wan, Chung, Kenny K. K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373518/
https://ncbi.nlm.nih.gov/pubmed/22701661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038545
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