Presynaptic Alpha-Synuclein Aggregation in a Mouse Model of Parkinson's Disease

Parkinson's disease and dementia with Lewy bodies are associated with abnormal neuronal aggregation of α-synuclein. However, the mechanisms of aggregation and their relationship to disease are poorly understood. We developed an in vivo multiphoton imaging paradigm to study α-synuclein aggregati...

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Bibliographic Details
Main Authors: Spinelli, Kateri J., Taylor, Jonathan K., Osterberg, Valerie R., Churchill, Madeline J., Pollock, Eden, Moore, Cynthia, Meshul, Charles K., Unni, Vivek K.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913861/
https://ncbi.nlm.nih.gov/pubmed/24501346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2581-13.2014
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