Alpha-Synuclein Preformed Fibrils Induce Cellular Senescence in Parkinson’s Disease Models

Emerging evidence indicates that cellular senescence could be a critical inducing factor for aging-associated neurodegenerative disorders. However, the involvement of cellular senescence remains unclear in Parkinson’s disease (PD). To determine this, we assessed the effects of α-synuclein preformed...

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Udgivet i:Cells
Main Authors: Verma, Dinesh Kumar, Seo, Bo Am, Ghosh, Anurupa, Ma, Shi-Xun, Hernandez-Quijada, Karina, Andersen, Julie K., Ko, Han Seok, Kim, Yong-Hwan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8304385/
https://ncbi.nlm.nih.gov/pubmed/34359864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071694
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