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GPCR expression in tissues and cells: Are the optimal receptors being used as drug targets?

G-protein-coupled receptors [GPCRs, also known as 7-transmembrane (7-TM) receptors] comprise the largest family of membrane receptors in humans and other species and, in addition, represent the greatest number of current drug targets. In this article, we review methods to define GPCR expression and...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Insel, PA, Snead, A, Murray, F, Zhang, L, Yokouchi, H, Katakia, T, Kwon, O, Dimucci, D, Wilderman, A
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Blackwell Publishing Ltd 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372817/
https://ncbi.nlm.nih.gov/pubmed/21488863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01434.x
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