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GPCR expression in tissues and cells: Are the optimal receptors being used as drug targets?

G-protein-coupled receptors [GPCRs, also known as 7-transmembrane (7-TM) receptors] comprise the largest family of membrane receptors in humans and other species and, in addition, represent the greatest number of current drug targets. In this article, we review methods to define GPCR expression and...

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Detalhes bibliográficos
Main Authors: Insel, PA, Snead, A, Murray, F, Zhang, L, Yokouchi, H, Katakia, T, Kwon, O, Dimucci, D, Wilderman, A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372817/
https://ncbi.nlm.nih.gov/pubmed/21488863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01434.x
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