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The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1
Interleukin-34 (IL-34) and colony stimulating factor-1 (CSF-1) both signal through the CSF-1R receptor tyrosine kinase, but they have no sequence homology, and their functions and signaling activities are not identical. We report the crystal structures of mouse IL-34 alone and in complex with the N-...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372767/ https://ncbi.nlm.nih.gov/pubmed/22579672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2012.04.012 |
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