IL-1 family cytokines use distinct molecular mechanisms to signal through their shared co-receptor

Within the interleukin 1 (IL-1) cytokine family, IL-1 receptor accessory protein (IL-1RAcP) is the co-receptor for eight receptor:cytokine pairs, including cytokines IL-1β and IL-33. Unlike for IL-1β, no structure of the IL-33 signaling complex exists that includes both its cognate receptor, ST2, an...

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Publicado no:Immunity
Main Authors: Günther, Sebastian, Deredge, Daniel, Bowers, Amanda L., Luchini, Alessandra, Bonsor, Daniel A., Beadenkopf, Robert, Liotta, Lance, Wintrode, Patrick L., Sundberg, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849085/
https://ncbi.nlm.nih.gov/pubmed/28930661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.08.004
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