The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

Interleukin (IL)-1 family cytokines potently regulate inflammation, with the majority of the IL-1 family proteins being secreted from immune cells via unconventional pathways. In many cases, secretion of IL-1 cytokines appears to be closely coupled to cell death, yet the secretory mechanisms involve...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Tapia, Victor S., Daniels, Michael J. D., Palazón-Riquelme, Pablo, Dewhurst, Matthew, Luheshi, Nadia M., Rivers-Auty, Jack, Green, Jack, Redondo-Castro, Elena, Kaldis, Philipp, Lopez-Castejon, Gloria, Brough, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544845/
https://ncbi.nlm.nih.gov/pubmed/30940725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008009
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