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Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family
The heterodimeric IL-12 cytokine family is characterized by the sharing of three α (p19, p28, p35) and two β (p40 and Ebi3) subunits, and includes IL-12 (p35/p40), IL-23 (p19/p40), IL-27 (p28/Ebi3) and IL-35 (p35/Ebi3). In this study, the dimerization interfaces of IL-12 family members were characte...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341524/ https://ncbi.nlm.nih.gov/pubmed/22487722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.03.025 |
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