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Structural Basis of IL-1 Family Cytokine Signaling

Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli. The basic mechanism of signal initiation is a stepwise process in which an agonist cytokine binds its cognate receptor. Tog...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Fields, James K., Günther, Sebastian, Sundberg, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596353/
https://ncbi.nlm.nih.gov/pubmed/31281320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01412
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