Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

CSF-1 is broadly expressed and regulates macrophage and osteoclast development. The action and expression of IL-34, a novel CSF-1R ligand, were investigated in the mouse. As expected, huIL-34 stimulated macrophage proliferation via the huCSF-1R, equivalently to huCSF-1, but was much less active at s...

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Detalhes bibliográficos
Main Authors: Wei, Suwen, Nandi, Sayan, Chitu, Violeta, Yeung, Yee-Guide, Yu, Wenfeng, Huang, Minmei, Williams, Lewis T., Lin, Haishan, Stanley, E. Richard
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Receptors, Signal Transduction, & Genes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924605/
https://ncbi.nlm.nih.gov/pubmed/20504948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1209822
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