Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

CSF-1 is broadly expressed and regulates macrophage and osteoclast development. The action and expression of IL-34, a novel CSF-1R ligand, were investigated in the mouse. As expected, huIL-34 stimulated macrophage proliferation via the huCSF-1R, equivalently to huCSF-1, but was much less active at s...

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Bibliographic Details
Main Authors:	Wei, Suwen, Nandi, Sayan, Chitu, Violeta, Yeung, Yee-Guide, Yu, Wenfeng, Huang, Minmei, Williams, Lewis T., Lin, Haishan, Stanley, E. Richard
Format:	Artigo
Language:	Inglês
Published:	The Society for Leukocyte Biology 2010
Subjects:	Receptors, Signal Transduction, & Genes
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2924605/ https://ncbi.nlm.nih.gov/pubmed/20504948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1209822
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Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

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