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CSF-1 receptor structure/function in MacCsf1r–/– macrophages: regulation of proliferation, differentiation, and morphology

CSF-1 is the major regulator of tissue macrophage development and function. A GM-CSF-dependent, CSF-1 receptor (CSF-1R)-deficient F4/80(hi)Mac-1(+)Gr1(–)CD11c(+) bone marrow macrophage (BMM) line (MacCsf1r−/−) was developed to study the roles of the eight intracellular CSF-1R tyrosines phosphorylate...

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Autores principales: Yu, Wenfeng, Chen, Jian, Xiong, Ying, Pixley, Fiona J., Dai, Xu-Ming, Yeung, Yee-Guide, Stanley, E. Richard
Formato: Artigo
Lenguaje:Inglês
Publicado: The Society for Leukocyte Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516905/
https://ncbi.nlm.nih.gov/pubmed/18519746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0308171
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