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Macrophage Proliferation Is Regulated through CSF-1 Receptor Tyrosines 544, 559, and 807
Colony-stimulating factor-1 (CSF-1)-stimulated CSF-1 receptor (CSF-1R) tyrosine phosphorylation initiates survival, proliferation, and differentiation signaling pathways in macrophages. Either activation loop Y807F or juxtamembrane domain (JMD) Y559F mutations severely compromise CSF-1-regulated pro...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340183/ https://ncbi.nlm.nih.gov/pubmed/22375015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.355610 |
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