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Histone Demethylase UTX and Chromatin Remodeler BRM Bind Directly to CBP and Modulate Acetylation of Histone H3 Lysine 27

Trithorax group (TrxG) proteins antagonize Polycomb silencing and are required for maintenance of transcriptionally active states. We previously showed that the Drosophila melanogaster acetyltransferase CREB-binding protein (CBP) acetylates histone H3 lysine 27 (H3K27ac), thereby directly blocking i...

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Bibliografiske detaljer
Main Authors: Tie, Feng, Banerjee, Rakhee, Conrad, Patricia A., Scacheri, Peter C., Harte, Peter J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372260/
https://ncbi.nlm.nih.gov/pubmed/22493065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06392-11
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