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Histone Demethylase UTX and Chromatin Remodeler BRM Bind Directly to CBP and Modulate Acetylation of Histone H3 Lysine 27

Trithorax group (TrxG) proteins antagonize Polycomb silencing and are required for maintenance of transcriptionally active states. We previously showed that the Drosophila melanogaster acetyltransferase CREB-binding protein (CBP) acetylates histone H3 lysine 27 (H3K27ac), thereby directly blocking i...

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Autores principales: Tie, Feng, Banerjee, Rakhee, Conrad, Patricia A., Scacheri, Peter C., Harte, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372260/
https://ncbi.nlm.nih.gov/pubmed/22493065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06392-11
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