Deep Sequencing Reveals Minor Protease Resistance Mutations in Patients Failing a Protease Inhibitor Regimen

Standard genotypic antiretroviral resistance testing, performed by bulk sequencing, does not readily detect variants that comprise <20% of the circulating HIV-1 RNA population. Nevertheless, it is valuable in selecting an antiretroviral regimen after antiretroviral failure. In patients with poor...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fisher, Randall, van Zyl, Gert U., Travers, Simon A. A., Kosakovsky Pond, Sergei L., Engelbrech, Susan, Murrell, Ben, Scheffler, Konrad, Smith, Davey
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372173/
https://ncbi.nlm.nih.gov/pubmed/22457522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06541-11
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados