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Detecting Individual Sites Subject to Episodic Diversifying Selection

The imprint of natural selection on protein coding genes is often difficult to identify because selection is frequently transient or episodic, i.e. it affects only a subset of lineages. Existing computational techniques, which are designed to identify sites subject to pervasive selection, may fail t...

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Bibliografiske detaljer
Main Authors: Murrell, Ben, Wertheim, Joel O., Moola, Sasha, Weighill, Thomas, Scheffler, Konrad, Kosakovsky Pond, Sergei L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395634/
https://ncbi.nlm.nih.gov/pubmed/22807683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002764
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