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On the Validity of Evolutionary Models with Site-Specific Parameters

Evolutionary models that make use of site-specific parameters have recently been criticized on the grounds that parameter estimates obtained under such models can be unreliable and lack theoretical guarantees of convergence. We present a simulation study providing empirical evidence that a simple ve...

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Bibliografiske detaljer
Main Authors: Scheffler, Konrad, Murrell, Ben, Kosakovsky Pond, Sergei L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983186/
https://ncbi.nlm.nih.gov/pubmed/24722425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094534
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