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Correcting the Bias of Empirical Frequency Parameter Estimators in Codon Models
Markov models of codon substitution are powerful inferential tools for studying biological processes such as natural selection and preferences in amino acid substitution. The equilibrium character distributions of these models are almost always estimated using nucleotide frequencies observed in a se...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912764/ https://ncbi.nlm.nih.gov/pubmed/20689581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011230 |
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