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Acidosis Differentially Modulates Inactivation in Na(V)1.2, Na(V)1.4, and Na(V)1.5 Channels
Na(V) channels play a crucial role in neuronal and muscle excitability. Using whole-cell recordings we studied effects of low extracellular pH on the biophysical properties of Na(V)1.2, Na(V)1.4, and Na(V)1.5, expressed in cultured mammalian cells. Low pH produced different effects on different chan...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Research Foundation
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372088/ https://ncbi.nlm.nih.gov/pubmed/22701426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00109 |
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