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Identification of sequence–structure RNA binding motifs for SELEX-derived aptamers

Motivation: Systematic Evolution of Ligands by EXponential Enrichment (SELEX) represents a state-of-the-art technology to isolate single-stranded (ribo)nucleic acid fragments, named aptamers, which bind to a molecule (or molecules) of interest via specific structural regions induced by their sequenc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoinka, Jan, Zotenko, Elena, Friedman, Adam, Sauna, Zuben E., Przytycka, Teresa M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371842/
https://ncbi.nlm.nih.gov/pubmed/22689764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts210
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