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AptaCluster - A Method to Cluster HT-SELEX Aptamer Pools and Lessons from its Application

Systematic Evolution of Ligands by EXponential Enrichment (SELEX) is a well established experimental procedure to identify aptamers - synthetic single-stranded (ribo)nucleic molecules that bind to a given molecular target. Recently, new sequencing technologies have revolutionized the SELEX protocol...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Res Comput Mol Biol
Prif Awduron: Hoinka, Jan, Berezhnoy, Alexey, Sauna, Zuben E., Gilboa, Eli, Przytycka, Teresa M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281958/
https://ncbi.nlm.nih.gov/pubmed/25558474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-05269-4_9
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