AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments

Aptamers, short RNA or DNA molecules that bind distinct targets with high affinity and specificity, can be identified using High Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX). But scalable analytic tools for understanding sequence-function relationships from diverse...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Syst
Prif Awduron: Dao, Phuong, Hoinka, Jan, Takahashi, Mayumi, Zhou, Jiehua, Ho, Michelle, Wang, Yijie, Costa, Fabrizio, Rossi, John J., Backofen, Rolf, Burnett, John, Przytycka, Teresa M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042215/
https://ncbi.nlm.nih.gov/pubmed/27467247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.07.003
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