AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments

Aptamers, short RNA or DNA molecules that bind distinct targets with high affinity and specificity, can be identified using High Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX). But scalable analytic tools for understanding sequence-function relationships from diverse...

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發表在:Cell Syst
Main Authors: Dao, Phuong, Hoinka, Jan, Takahashi, Mayumi, Zhou, Jiehua, Ho, Michelle, Wang, Yijie, Costa, Fabrizio, Rossi, John J., Backofen, Rolf, Burnett, John, Przytycka, Teresa M.
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042215/
https://ncbi.nlm.nih.gov/pubmed/27467247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.07.003
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