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AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments

Aptamers, short RNA or DNA molecules that bind distinct targets with high affinity and specificity, can be identified using High Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX). But scalable analytic tools for understanding sequence-function relationships from diverse...

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Bibliografiske detaljer
Udgivet i:Cell Syst
Main Authors: Dao, Phuong, Hoinka, Jan, Takahashi, Mayumi, Zhou, Jiehua, Ho, Michelle, Wang, Yijie, Costa, Fabrizio, Rossi, John J., Backofen, Rolf, Burnett, John, Przytycka, Teresa M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042215/
https://ncbi.nlm.nih.gov/pubmed/27467247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.07.003
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