AptaTRACE Elucidates RNA Sequence-Structure Motifs from Selection Trends in HT-SELEX Experiments

Aptamers, short RNA or DNA molecules that bind distinct targets with high affinity and specificity, can be identified using High Throughput Systematic Evolution of Ligands by Exponential Enrichment (HT-SELEX). But scalable analytic tools for understanding sequence-function relationships from diverse...

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Publicado en:Cell Syst
Main Authors: Dao, Phuong, Hoinka, Jan, Takahashi, Mayumi, Zhou, Jiehua, Ho, Michelle, Wang, Yijie, Costa, Fabrizio, Rossi, John J., Backofen, Rolf, Burnett, John, Przytycka, Teresa M.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042215/
https://ncbi.nlm.nih.gov/pubmed/27467247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.07.003
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