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Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery
High-Throughput (HT) SELEX combines SELEX (Systematic Evolution of Ligands by EXponential Enrichment), a method for aptamer discovery, with massively parallel sequencing technologies. This emerging technology provides data for a global analysis of the selection process and for simultaneous discovery...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4499121/ https://ncbi.nlm.nih.gov/pubmed/25870409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv308 |
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