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Weighted pooling—practical and cost-effective techniques for pooled high-throughput sequencing
Motivation: Despite the rapid decline in sequencing costs, sequencing large cohorts of individuals is still prohibitively expensive. Recently, several sophisticated pooling designs were suggested that can identify carriers of rare alleles in large cohorts with a significantly smaller number of pools...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371840/ https://ncbi.nlm.nih.gov/pubmed/22689761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts208 |
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