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Weighted pooling—practical and cost-effective techniques for pooled high-throughput sequencing
Motivation: Despite the rapid decline in sequencing costs, sequencing large cohorts of individuals is still prohibitively expensive. Recently, several sophisticated pooling designs were suggested that can identify carriers of rare alleles in large cohorts with a significantly smaller number of pools...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371840/ https://ncbi.nlm.nih.gov/pubmed/22689761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts208 |
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