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Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

Llamas (Lama glama) naturally produce heavy chain–only antibodies (Abs) in addition to conventional Abs. The variable regions (VHH) in these heavy chain–only Abs demonstrate comparable affinity and specificity for antigens to conventional immunoglobulins despite their much smaller size. To date, imm...

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מידע ביבליוגרפי
Main Authors: McCoy, Laura E., Quigley, Anna Forsman, Strokappe, Nika M., Bulmer-Thomas, Bianca, Seaman, Michael S., Mortier, Daniella, Rutten, Lucy, Chander, Nikita, Edwards, Carolyn J., Ketteler, Robin, Davis, David, Verrips, Theo, Weiss, Robin A.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371729/
https://ncbi.nlm.nih.gov/pubmed/22641382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20112655
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