Llama Antibody Fragments Recognizing Various Epitopes of the CD4bs Neutralize a Broad Range of HIV-1 Subtypes A, B and C

Many of the neutralising antibodies, isolated to date, display limited activities against the globally most prevalent HIV-1 subtypes A and C. Therefore, those subtypes are considered to be an important target for antibody-based therapy. Variable domains of llama heavy chain antibodies (VHH) have som...

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Hauptverfasser: Strokappe, Nika, Szynol, Agnieszka, Aasa-Chapman, Marlèn, Gorlani, Andrea, Forsman Quigley, Anna, Hulsik, David Lutje, Chen, Lei, Weiss, Robin, de Haard, Hans, Verrips, Theo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3305327/
https://ncbi.nlm.nih.gov/pubmed/22438910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033298
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