Coding exons function as tissue-specific enhancers of nearby genes

Enhancers are essential gene regulatory elements whose alteration can lead to morphological differences between species, developmental abnormalities, and human disease. Current strategies to identify enhancers focus primarily on noncoding sequences and tend to exclude protein coding sequences. Here,...

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Bibliografski detalji
Glavni autori: Birnbaum, Ramon Y., Clowney, E. Josephine, Agamy, Orly, Kim, Mee J., Zhao, Jingjing, Yamanaka, Takayuki, Pappalardo, Zachary, Clarke, Shoa L., Wenger, Aaron M., Nguyen, Loan, Gurrieri, Fiorella, Everman, David B., Schwartz, Charles E., Birk, Ohad S., Bejerano, Gill, Lomvardas, Stavros, Ahituv, Nadav
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2012
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371700/
https://ncbi.nlm.nih.gov/pubmed/22442009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133546.111
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