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Exonic enhancers: proceed with caution in exome and genome sequencing studies

Exonic enhancers (eExons) are coding exons that also function as enhancers of the gene in which they reside or (a) nearby gene(s). Mutations that affect the enhancer activity of these eExons have been associated with human disease. Therefore, eExon mutations should be taken into account in exome and...

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Detalhes bibliográficos
Publicado no:Genome Med
Autor principal: Ahituv, Nadav
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745165/
https://ncbi.nlm.nih.gov/pubmed/26856702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0277-0
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