Coding exons function as tissue-specific enhancers of nearby genes

Enhancers are essential gene regulatory elements whose alteration can lead to morphological differences between species, developmental abnormalities, and human disease. Current strategies to identify enhancers focus primarily on noncoding sequences and tend to exclude protein coding sequences. Here,...

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書誌詳細
主要な著者: Birnbaum, Ramon Y., Clowney, E. Josephine, Agamy, Orly, Kim, Mee J., Zhao, Jingjing, Yamanaka, Takayuki, Pappalardo, Zachary, Clarke, Shoa L., Wenger, Aaron M., Nguyen, Loan, Gurrieri, Fiorella, Everman, David B., Schwartz, Charles E., Birk, Ohad S., Bejerano, Gill, Lomvardas, Stavros, Ahituv, Nadav
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2012
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371700/
https://ncbi.nlm.nih.gov/pubmed/22442009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133546.111
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